The Four Factors That Influence Biological Aging

The Four Factors That Influence Biological Aging

Investigators determined that only three of the five criteria for biological aging significantly interacted in humans to the point that an increase in one indicator also matched an increase in another. Additionally, measurements of epigenetics, gene levels and proteomics linked depression to more advanced aging, which suggested that mental and physical health affect biological age. “Our work suggests that biological aging indicators largely track distinct but partially overlapping aspects of the aging process,” said Brenda Penninx, PhD, a professor of psychiatric epidemiology at Amsterdam UMC and the study’s senior author. “Taken together, our findings contribute to the understanding and identification of biological age determinants—important for the development of outcomes for clinical and population-based research,” she added. For related coverage read, “Despite His Advanced Age, Justin Gatlin is a Peak Performer” and “Smoking May Speed Up Your Biological Clock.”

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