Popular Genome Editing Tool Gets Its Close-Up

Popular Genome Editing Tool Gets Its Close-Up

Since then, X-ray crystallography has been used to chart a vast number of biological structures, including those of DNA, proteins, and even whole viruses. The Cas9 enzyme was originally discovered in bacteria. Armed with the new crystal structure, Zhang’s team can now determine which regions of the enzyme are essential for editing DNA and which parts might be dispensable. The NIH grantee received the award for her pioneering role in the 2012 discovery of the CRISPR gene-editing technique. (NIH Common Fund)NIH support: Office of the Director (Common Fund); National Institute of Mental Health; National Institute of General Medical Sciences

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