J&J COVID-19 Vaccine Is 72% Effective After a Single Dose in U.S. Study

J&J COVID-19 Vaccine Is 72% Effective After a Single Dose in U.S. Study

The J&J vaccine requires only a single injection, doubling the number of people who can be vaccinated with a given supply. The J&J vaccine uses a weakened human adenovirus—similar to viruses that cause the common cold—as a vector to deliver genes encoding the SARS-CoV-2 spike protein. An interim analysis showed that the vaccine was 66% effective overall at preventing moderate and severe COVID-19 at 28 days after the single dose. The J&J vaccine was well tolerated with no significant safety concerns, according to the company. COVID-19 vaccines from other companies produce antibody levels similar to or several times higher than those resulting from natural infection.

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