Argentine Woman Appears Free of HIV Long After Stopping Treatment

Argentine Woman Appears Free of HIV Long After Stopping Treatment

While antiretroviral therapy can keep HIV suppressed during treatment, it is very difficult to cure. Two weeks after treatment initiation, her viral load was 2,200, and her CD4 T-cell count was 164—below the threshold for an AIDS diagnosis. The woman experienced treatment failure a year later and switched to d4T (stavudine, or Zerit), lamivudine (3TC, or Epivir) and indinavir (Crixivan). Despite stopping treatment, her viral load has remained suppressed ever since, and she continues to maintain a stable CD4 count in the 500 to 900 range. The woman shows only minimal HIV-specific CD8 T-cell responses, indicating that her immune system is not actively fighting the virus—unlike the robust T-cell responses typically seen in elite controllers.

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