Protein Mapping Study Reveals Valuable Clues for COVID-19 Drug Development

Protein Mapping Study Reveals Valuable Clues for COVID-19 Drug Development

Protein Mapping Study Reveals Valuable Clues for COVID-19 Drug DevelopmentPosted on October 27th, 2020 by Dr. Francis CollinsCredit: DE Gordon et al., Science, 2020One way to fight COVID-19 is with drugs that directly target SARS-CoV-2, the novel coronavirus that causes the disease. But researchers discovered that Orf9b dissociates into a single molecule (orange) when it interacts with the human protein TOM70 (teal). This is just one intriguing example out of 389 interactions between SARS-CoV-2 and human proteins uncovered in the new study. These studies narrowed the list to 73 human proteins that the virus depends on to replicate. Reference:[1] Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

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