NIH Study Aims To Identify Promising COVID-19 Treatments for Larger Trials

NIH Study Aims To Identify Promising COVID-19 Treatments for Larger Trials

Approximately 100 hospitalized volunteers will be assigned to each study arm with each of the study sites testing no more than three investigational treatments at once. Remdesivir has demonstrated clinical benefit for patients with severe COVID-19 requiring supplemental oxygen and is considered standard of care for hospitalized COVID-19 patients. Lenzilumab is currently being tested separately in a phase 3 COVID-19 study and in a phase 1b/2 study as sequenced therapy with CAR-T treatments. In the ACTIV-5/BET study, volunteers assigned to receive risankizumab will be administered a single intravenous dose on day one of the study. For more information about the ACTIV-5/BET trial, please visit ClinicalTrials.gov using the identifier NCT04583969.

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