Inherited Risk of Early-Onset Cancer Higher Among Racial Minorities

Inherited Risk of Early-Onset Cancer Higher Among Racial Minorities

“Cancer clustering within families, meaning the devastating diagnosis of more than one early-onset cancer within the same family, usually points to a genetic cause. We found that family-based cancer clustering occurs more frequently among minority populations.”Researchers used California population-based health registries to evaluate the relative cancer risk among parents, siblings and children of patients diagnosed with cancer by the age of 26. Between 1989 and 2015, they identified 29,632 early-onset cancer patients and then examined cancer incidence in 62,863 healthy family members. They found that overall, mothers and siblings of those cancer patients had a higher relative risk of early onset cancer. This study demonstrates the need for increased scrutiny on familial cancer clustering in minority populations.

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