Finding Antibodies that Neutralize SARS-CoV-2

Finding Antibodies that Neutralize SARS-CoV-2

Finding Antibodies that Neutralize SARS-CoV-2Posted on June 30th, 2020 by Dr. Francis CollinsCaption: Model of three neutralizing antibodies (blue, purple and orange) bound to the spike protein, which allows SARS-CoV-2 attach to our cells. The study, published in the journal Nature, shows that most people, in fact, do produce antibodies that can effectively neutralize SARS-CoV-2. By mass-producing copies of these antibodies as so-called monoclonal antibodies, the researchers can now better evaluate their potential as treatments to help people who don’t make strongly neutralizing antibodies, or not enough of them. Among these two “elite responders” and four other individuals, the researchers identified 40 different antibodies that could neutralize SARS-CoV-2. If a candidate vaccine can generate such strongly neutralizing antibodies, researchers will know that they are on the right track.

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