At the Forefront of COVID-19 Host Genomics, with Leslie Biesecker, NHGRI

At the Forefront of COVID-19 Host Genomics, with Leslie Biesecker, NHGRI

Led by Andrea Ganna, PhD, and Mark Daly, PhD, at the Institute of Molecular Medicine, Finland, the COVID-19 Host Genetics Initiative currently has about 160 registered studies and partners. We sat down with ASHG Past President and NIH Distinguished Investigator Leslie Biesecker, MD, to discuss the efforts at the National Institutes of Health (NIH) in the Initiative. ASHG: How did you pivot your research to studying the genetic susceptibility to severe COVID-19 disease? Additional key factors that help our ability to do this rapidly are the nimbleness of the intramural research program and the available resources at the National Human Genome Research Institute (NHGRI). This case is very different, but both are examples of the broad utility of genetics and genomics to answer important questions.

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