Antiretrovirals for HIV Don’t Raise Birth Defect Risk

Antiretrovirals for HIV Don’t Raise Birth Defect Risk

Since 1989, the Antiretroviral Pregnancy Registry has been a repository for information about women with HIV, the antiretroviral (ARV) regimen they are taking and their pregnancy outcomes. The registry tracks incidents of birth defects by trimester and by specific drug to catch any signals of an increased rate of birth defects after clinical trials are completed. So researcher William Short, MD, of the Perelman School of Medicine at the University of Pennsylvania, and colleagues used the registry’s database to assess risk for birth defects among children born to women on HIV treatment. What’s more, there were no variations in rates of birth defects by trimester: 2.8% in the first trimester and 2.8% in the second and third trimester combined. However, because the registry is voluntary, it’s likely the findings don’t reflect all live births for women using HIV treatment during pregnancy.

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